Cognitive and other neuropsychological profiles in children with newly diagnosed benign rolandic epilepsy
Open Access
- 1 January 2012
- journal article
- Published by Korean Pediatric Society in Korean Journal of Pediatrics
- Vol. 55 (10), 383-387
- https://doi.org/10.3345/kjp.2012.55.10.383
Abstract
Although benign rolandic epilepsy (BRE) is a benign condition, it may be associated with a spectrum of behavioral, psychiatric, and cognitive disorders. This study aimed to assess the cognitive and other neuropsychological profiles of children with BRE. In total, 23 children with BRE were consecutively recruited. All children underwent sleep electroencephalography (EEG) and were assessed on a battery of comprehensive neuropsychological tests including the Korean versions of the Wechsler intelligence scale for children III, frontal executive neuropsychological test, rey complex figure test, Wisconsin card sorting test, attention deficit diagnostic scale, and child behavior checklist scale. The study subjects included 13 boys and 10 girls aged 9.0±1.6 years. Our subjects showed an average monthly seizure frequency of 0.9±0.7, and a majority of them had focal seizures (70%). The spike index (frequency/min) was 4.1±5.3 (right) and 13.1±15.9 (left). Of the 23 subjects, 9 showed frequent spikes (>10/min) on the EEG. The subjects had normal cognitive and frontal executive functions, memory, and other neuropsychological sub-domain scores, even though 8 children (35%) showed some evidence of learning difficulties, attention deficits, and aggressive behavior. Our data have limited predictive value; however, these data demonstrate that although BRE appears to be benign at the onset, children with BRE might develop cognitive, behavioral, and other psychiatric disorders during the active phase of epilepsy, and these problems may even outlast the BRE. Therefore, we recommend scrupulous follow-up for children with BRE.Keywords
This publication has 26 references indexed in Scilit:
- Cognitive and linguistic abnormalities in benign childhood epilepsy with centrotemporal spikesActa Paediatrica, 2011
- Neuropsychological aspects of benign childhood epilepsy with centrotemporal spikesSeizure, 2010
- Cognitive deficits in children with benign rolandic epilepsy of childhood or rolandic discharges: A study of children between 4 and 7 years of age with and without seizures compared with healthy controlsEpilepsy & Behavior, 2009
- Neuropsychologic Impairment in Children With Rolandic EpilepsyPediatric Neurology, 2009
- The combined burden of cognitive, executive function, and psychosocial problems in children with epilepsy: a population‐based studyDevelopmental Medicine and Child Neurology, 2008
- Deterioration in Cognitive Function in Children With Benign Epilepsy of Childhood With Central Temporal Spikes Treated With SulthiameJournal of Child Neurology, 2007
- Clinical evaluation of attentional processes in children with benign childhood epilepsy with centrotemporal spikes (BCECTS)Epileptic Disorders, 2007
- The consequences of idiopathic partial epilepsies in relation to neuropsychological functioning: a closer look at the associated mathematical disabilityEpileptic Disorders, 2006
- Cognitive and behavioral effects of nocturnal epileptiform discharges in children with benign childhood epilepsy with centrotemporal spikesEpilepsy & Behavior, 2006
- Educational problems with underlying neuropsychological impairment are common in children with Benign Epilepsy of Childhood with Centrotemporal Spikes (BECTS)Seizure, 2005