A Small Molecule Inhibitor, 1,2,4,5-Benzenetetraamine Tetrahydrochloride, Targeting the Y397 Site of Focal Adhesion Kinase Decreases Tumor Growth
- 7 November 2008
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Medicinal Chemistry
- Vol. 51 (23), 7405-7416
- https://doi.org/10.1021/jm800483v
Abstract
No abstract availableKeywords
This publication has 23 references indexed in Scilit:
- Antitumor Activity and Pharmacology of a Selective Focal Adhesion Kinase Inhibitor, PF-562,271Cancer Research, 2008
- Therapeutic Efficacy of a Novel Focal Adhesion Kinase Inhibitor TAE226 in Ovarian CarcinomaCancer Research, 2007
- p53 regulates FAK expression in human tumor cellsMolecular Carcinogenesis, 2007
- TAE226‐Induced apoptosis in breast cancer cells with overexpressed Src or EGFRMolecular Carcinogenesis, 2007
- Cellular Characterization of a Novel Focal Adhesion Kinase InhibitorJournal of Biological Chemistry, 2007
- N-MYC Regulates Focal Adhesion Kinase Expression in Human NeuroblastomaPublished by Elsevier BV ,2007
- Focal Adhesion Kinase and p53 Signaling in Cancer CellsInternational Review of Cytology, 2007
- Dual Inhibition of Focal Adhesion Kinase and Epidermal Growth Factor Receptor Pathways Cooperatively Induces Death Receptor-mediated Apoptosis in Human Breast Cancer CellsPublished by Elsevier BV ,2002
- The Focal Adhesion Kinase Suppresses Transformation-associated, Anchorage-independent Apoptosis in Human Breast Cancer CellsPublished by Elsevier BV ,2000
- Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src.Molecular and Cellular Biology, 1994