Pulses and lipaemia, short- and long-term effect: Potential in the prevention of cardiovascular disease
Open Access
- 1 December 2002
- journal article
- research article
- Published by Cambridge University Press (CUP) in British Journal of Nutrition
- Vol. 88 (S3), 263-271
- https://doi.org/10.1079/bjn2002716
Abstract
Cardiovascular disease (CVD) is the leading cause of death in most developed countries. Most CVD deaths are preventable through life-style measures such as diet, exercise and avoidance of cigarette smoking. Decreased intake of saturated fat and cholesterol and increased intake of cholesterol-reducing foods, such as pulses, deserve a high priority for activities designed to prevent CVD. Epidemiological and observational studies indicate that habitual intakes of large amounts of dietary fibre or of vegetables are associated with significantly lower rates of CVD. Studies over four decades document the hypocholesterolaemic effect of pulses and soyabeans. We performed a meta-analysis of eleven clinical trials that examined the effects of pulses (not including soyabeans) on serum lipoproteins. Intake of non-soya pulses was associated with these changes: fasting serum cholesterol, –7·2%, 95% CI –5·8, –8·6%; LDL–cholesterol, –6·2%, 95% CI –2·8, –9·5%; HDL–cholesterol, +2·6%, 95% CI +6·3, –1·0%; triacylglycerols, –16·6 %, 95% CI –11·8 %, –21·5 %; and body weight, –20·9%, 95% CI +2·2%, –4·1%. The hypocholesterolaemic effects of pulses appear related, in estimated order of importance, to these factors: soluble dietary fibre, vegetable protein, oligosaccharides, isoflavones, phospholipids and fatty acids, saponins and other factors. Intake of pulses may also reduce risk for CVD by favourable effects on blood pressure, glycaemia and risk for diabetes, and risk for obesity. Overall, the available evidence indicates that regular consumption of pulses may have important protective effects on risk for CVD.Keywords
This publication has 76 references indexed in Scilit:
- Trends in the Incidence of Coronary Heart Disease and Changes in Diet and Lifestyle in WomenThe New England Journal of Medicine, 2000
- Whole‐grain consumption and chronic disease: Protective mechanismsNutrition and Cancer, 1997
- Nutrition and health implications of dry beans: a review.Journal of the American College of Nutrition, 1994
- Soluble fiber and serum lipids: A literature reviewJournal of the American Dietetic Association, 1994
- Guar GumDrugs, 1990
- Dietary fiber and coronary heart diseaseCritical Reviews in Food Science and Nutrition, 1990
- The effect of daily baked bean (Phaseolus vulgaris) consumption on the plasma lipid levels of young, normo-cholesterolaemic menBritish Journal of Nutrition, 1989
- Effect of guar gum on body-weight, hunger ratings and metabolism in obese subjectsBritish Journal of Nutrition, 1984
- Dietary management of obesity: evaluation of the time-energy displacement diet in terms of its efficacy and nutritional adequacy for long-term weight controlBritish Journal of Nutrition, 1982
- Bulking Agents in the Treatment of ObesityAnnals of Nutrition and Metabolism, 1975