Green tea consumption and gastric cancer in Japanese: a pooled analysis of six cohort studies

Abstract
Background: Previous experimental studies have suggested many possible anti-cancer mechanisms for green tea, but epidemiological evidence for the effect of green tea consumption on gastric cancer risk is conflicting. Objective: To examine the association between green tea consumption and gastric cancer. Methods: We analysed original data from six cohort studies that measured green tea consumption using validated questionnaires at baseline. Hazard ratios (HRs) in the individual studies were calculated, with adjustment for a common set of variables, and combined using a random-effects model. Results: During 2 285 968 person-years of follow-up for a total of 219 080 subjects, 3577 cases of gastric cancer were identified. Compared with those drinking Conclusions: Green tea may decrease the risk of distal gastric cancer in women.