Synthesis and pharmacological evaluation of thieno[2,3-b]pyridine derivatives as novel c-Src inhibitors
- 15 April 2011
- journal article
- Published by Elsevier BV in Bioorganic & Medicinal Chemistry
- Vol. 19 (8), 2517-2528
- https://doi.org/10.1016/j.bmc.2011.03.021
Abstract
No abstract availableKeywords
This publication has 27 references indexed in Scilit:
- Src Promotes Survival and Invasion of Lung Cancers with Epidermal Growth Factor Receptor Abnormalities and Is a Potential Candidate for Molecular-Targeted TherapyMolecular Cancer Research, 2009
- SRC family kinases as potential therapeutic targets for malignancies and immunological disorders.Current Medicinal Chemistry, 2008
- Inhibition of c-Src expression and activation in malignant pleural mesothelioma tissues leads to apoptosis, cell cycle arrest, and decreased migration and invasionMolecular Cancer Therapeutics, 2007
- 4-Anilino-7,8-dialkoxybenzo[g]quinoline-3-carbonitriles as Potent Src Kinase InhibitorsJournal of Medicinal Chemistry, 2005
- The Src Kinase Pathway Promotes Tamoxifen Agonist Action in Ishikawa Endometrial Cells through Phosphorylation-Dependent Stabilization of Estrogen Receptor α Promoter Interaction and Elevated Steroid Receptor Coactivator 1 ActivityMolecular Endocrinology, 2005
- Src tyrosine kinase promotes survival and resistance to chemotherapeutics in a mouse ovarian cancer cell lineBiochemical and Biophysical Research Communications, 2003
- Src kinase contributes to the metastatic spread of carcinoma cellsOncogene, 2002
- Elevated activity and expression of Src-family kinases in human breast carcinoma tissue versus matched non-tumor tissueZeitschrift für Krebsforschung und Klinische Onkologie, 2001
- Induction and regulation of epithelial–mesenchymal transitionsBiochemical Pharmacology, 2000
- The natural history, skeletal complications, and management of bone metastases in patients with prostate carcinomaCancer, 2000