Origins of the 1988 North American Drought
- 23 December 1988
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 242 (4886), 1640-1645
- https://doi.org/10.1126/science.242.4886.1640
Abstract
The contributions of two subclasses of excitatory amino acid transmitter receptors to the induction and expression of long-term potentiation (LTP) were analyzed in hippocampal slices. The quisqualate/kainate receptor antagonist DNQX (6,7-dinitro-quinoxaline-2,3-dione) blocked 85% of the evoked field potential, leaving a small response that was sensitive to D-AP5 (D-2-amino-5-phosphonopentanoate), an N-methyl-D-aspartate (NMDA) receptor blocker. This residual D-AP5-sensitive response was of comparable size in control and previously potentiated inputs. High-frequency stimulation in the presence of DNQX did not result in the development of robust LTP. Washout of the drug, however, revealed the potentiation effect. Thus NMDA-mediated responses can induce, but are not greatly affected by, LTP; non-NMDA receptors, conversely, mediate responses that are not needed to elicit LTP but that are required for its expression.Keywords
This publication has 26 references indexed in Scilit:
- 4.10. The Israel Space AgencyCOSPAR Information Bulletin, 1988
- The Greenhouse Theory of Climate Change: A Test by an Inadvertent Global ExperimentScience, 1988
- Sensitivity of Soil Moisture to Doubling of Carbon Dioxide in Climate Model Experiments. Part I: North AmericaJournal of Climate, 1988
- Reduction in Summer Soil Wetness Induced by an Increase in Atmospheric Carbon DioxideScience, 1986
- Meteorological Aspects of the El Niño/Southern OscillationScience, 1983
- Horizontal Energy propagation in a Barotropic Atmosphere with Meridional and Zonal StructureJournal of the Atmospheric Sciences, 1983
- Influence of Land-Surface Evapotranspiration on the Earth's ClimateScience, 1982
- Summer dryness due to an increase of atmospheric CO2 concentrationClimatic Change, 1981
- Seasonal Differences in the Stationary Response of a Linearized Primitive Equation Model: Prospects for Long-Range Weather Forecasting?Journal of the Atmospheric Sciences, 1980
- THE WEATHER AND CIRCULATION OF JUNE 19521Monthly Weather Review, 1952