Pot economy and one-pot synthesis
Top Cited Papers
Open Access
- 6 January 2016
- journal article
- perspective
- Published by Royal Society of Chemistry (RSC) in Chemical Science
- Vol. 7 (2), 866-880
- https://doi.org/10.1039/c5sc02913a
Abstract
The one-pot synthesis of a target molecule in the same reaction vessel is widely considered to be an efficient approach in synthetic organic chemistry. In this review, the characteristics and limitations of various one-pot syntheses of biologically active molecules are explained, primarily involving organocatalytic methods as key tactics. Besides catalysis, the pot-economy concepts presented herein are also applicable to organometallic and organic reaction methods in general.Keywords
Funding Information
- Ministry of Education, Culture, Sports, Science, and Technology
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