Further Insights into the Roles of GTP and the C Terminus of the Hepatitis C Virus Polymerase in the Initiation of RNA Synthesis
Open Access
- 1 October 2010
- journal article
- research article
- Published by Elsevier BV in Journal of Biological Chemistry
- Vol. 285 (43), 32906-32918
- https://doi.org/10.1074/jbc.m110.151316
Abstract
No abstract availableKeywords
This publication has 49 references indexed in Scilit:
- Replication of hepatitis C virusNature Reviews Microbiology, 2007
- Template requirements and binding of hepatitis C virus NS5B polymerase during in vitro RNA synthesis from the 3′-end of virus minus-strand RNAThe FEBS Journal, 2005
- Crystal Structures of the RNA-dependent RNA Polymerase Genotype 2a of Hepatitis C Virus Reveal Two Conformations and Suggest Mechanisms of Inhibition by Non-nucleoside InhibitorsJournal of Biological Chemistry, 2005
- Identification of the Hepatitis C Virus RNA Replication Complex in Huh-7 Cells Harboring Subgenomic RepliconsJournal of Virology, 2003
- Substrate Complexes of Hepatitis C Virus RNA Polymerase (HC-J4): Structural Evidence for Nucleotide Import and De-novo InitiationJournal of Molecular Biology, 2003
- The Hepatitis C Virus RNA-Dependent RNA Polymerase Membrane Insertion Sequence Is a Transmembrane SegmentJournal of Virology, 2002
- HCV RNA‐dependent RNA polymerase replicates in vitro the 3′ terminal region of the minus‐strand viral RNA more efficiently than the 3′ terminal region of the plus RNAEuropean Journal of Biochemistry, 2001
- A Novel Mechanism to Ensure Terminal Initiation by Hepatitis C Virus NS5B PolymeraseVirology, 2001
- Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virusProceedings of the National Academy of Sciences of the United States of America, 1999
- Crystal structure of the RNA-dependent RNA polymerase from hepatitis C virus reveals a fully encircled active site.Nature Structural & Molecular Biology, 1999