Anaphylactoid reactions and angioedema during alteplase treatment of acute ischemic stroke.
- 2 May 2000
- journal article
- case report
- Vol. 162 (9), 1281-4
Abstract
Among 105 patients given recombinant tissue plasminogen activator (rt-PA, alteplase) intravenously for acute stroke, 2 (1.9%) had lingual angioedema, which progressed to a fatal anaphylactoid reaction in 1. The authors review the 2 cases and possible mechanisms responsible. They warn that patients who are taking an angiotensin-converting-enzyme inhibitor may be at increased risk for angioedema with concomitant alteplase therapy.This publication has 22 references indexed in Scilit:
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