ACUTE ENERGY DEPRIVATION IN MAN - EFFECT ON CELL-MEDIATED IMMUNOLOGICAL REACTIONS
- 1 January 1976
- journal article
- research article
- Vol. 25 (2), 207-211
Abstract
The effects of 10 days of total energy deprivation on lymphocyte functions and cell-mediated immunity was evaluated in 14 healthy, normal-weighted males. Lymphocytes from 7 of the subjects were tested in vitro. A significant depression was noted in DNA synthesis after stimulation with pokeweed mitogen and PPD [purified protein derivative], while there was no effect on the response to concanavalin A. No change was noted in the percentages and total numbers of circulating B [bone marrow-derived] and T [thymus-derived] lymphocytes and monocytes. The delayed skin reactivity following intracutaneous PPD and mumps antigen was not different from non-starving control subjects.This publication has 17 references indexed in Scilit:
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