Behavioural activation v. antidepressant medication for treating depression in Iran: randomised trial
- 1 March 2013
- journal article
- research article
- Published by Royal College of Psychiatrists in The British Journal of Psychiatry
- Vol. 202 (3), 204-211
- https://doi.org/10.1192/bjp.bp.112.113696
Abstract
Background: Behavioural activation might be a viable alternative to antidepressant medication for major depressive disorder.Aims: To compare the effectiveness of behavioural activation and treatment as usual (TAU, antidepressant medication) for major depressive disorder in routine clinical practice in Iran.Method: Patients with major depressive disorder (n = 100) were randomised to 16 sessions of behavioural activation (n = 50) or antidepressant medication (n = 50) (IRCT138807192573N1). The main outcome was depression, measured with the Beck Depression inventory (BDI) and the Hamilton Rating Scale for Depression (HRSD), assessed at 0, 4, 13 and 49 weeks.Results: Symptom reduction was greater in the behavioural activation group than in the TAU group on both the BDI and the HRSD at 13 and 49 weeks in multilevel analysis. Baseline depression severity was a moderator, with relatively better effects for behavioural activation in individuals who were more severely depressed. Also, there was better retention in the behavioural activation than in the TAU group.Conclusions: Behavioural activation is a viable and effective treatment for people with major depressive disorder, especially for those who are more severely depressed, and it can successfully be disseminated into routine practice settings in a non-Western country such as Iran.This publication has 18 references indexed in Scilit:
- Diagnostic and Statistical Manual of Mental DisordersPsychiatry Research, 2011
- Behavioural activation delivered by the non-specialist: phase II randomised controlled trialThe British Journal of Psychiatry, 2011
- Randomized trial of behavioral activation, cognitive therapy, and antidepressant medication in the prevention of relapse and recurrence in major depression.Journal of Consulting and Clinical Psychology, 2008
- A meta-analysis of randomized trials of behavioural treatment of depressionPsychological Medicine, 2007
- Behavioral activation treatments of depression: A meta-analysisClinical Psychology Review, 2007
- National Trends in the Use of Outpatient PsychotherapyAmerican Journal of Psychiatry, 2002
- A brief behavioral activation treatment for depressionCognitive and Behavioral Practice, 2001
- Treatment guidelines for major depressive disorderBehavior Therapy, 2001
- A component analysis of cognitive-behavioral treatment for depression.Journal of Consulting and Clinical Psychology, 1996
- A RATING SCALE FOR DEPRESSIONJournal of Neurology, Neurosurgery & Psychiatry, 1960