Obesity and Lifestyle Management in Polycystic Ovary Syndrome
- 1 March 2007
- journal article
- Published by Ovid Technologies (Wolters Kluwer Health) in Clinical Obstetrics and Gynecology
- Vol. 50 (1), 277-294
- https://doi.org/10.1097/grf.0b013e31802f54c8
Abstract
Polycystic ovary syndrome is frequently associated with obesity, with at least 50% of women with polycystic ovary syndrome demonstrating overweight or obesity defined by body mass index >25 or >30 kg/m. Overweight and obesity impact the clinical reproductive and metabolic features of the syndrome. Long-term complications of obesity such as cardiovascular risk and diabetes, as well as those over the short term in reproductive function, are significantly improved by lifestyle modification. Weight reduction is difficult to achieve over the long-term and programs designed for modest reduction in overall body weight (5% to 10%) with improvements in fitness are as effective as severe weight reduction in reducing metabolic disease and improving ovulatory potential. Further research is needed into the best approach for successful interventions that result in long-term sustained weight loss.Keywords
This publication has 67 references indexed in Scilit:
- Prevalence of Overweight and Obesity in the United States, 1999-2004JAMA, 2006
- Commentary: Weight gain, weight loss, and endometrial cancerInternational Journal of Epidemiology, 2006
- Phenotypic Variation in Hyperandrogenic Women Influences the Findings of Abnormal Metabolic and Cardiovascular Risk ParametersJournal of Clinical Endocrinology & Metabolism, 2005
- The nutrition transition: worldwide obesity dynamics and their determinantsInternational Journal of Obesity, 2004
- The Prevalence and Features of the Polycystic Ovary Syndrome in an Unselected PopulationJournal of Clinical Endocrinology & Metabolism, 2004
- Genetic and environmental aspect of polycystic ovary syndromeJournal of Endocrinological Investigation, 2003
- Prevalence and Trends in Overweight Among US Children and Adolescents, 1999-2000Jama-Journal Of The American Medical Association, 2002
- DIFFERENCES IN CLINICAL AND ENDOCRINE FEATURES BETWEEN OBESE AND NON‐OBESE SUBJECTS WITH POLYCYSTIC OVARY SYNDROME: AN ANALYSIS OF 263 CONSECUTIVE CASESClinical Endocrinology, 1990
- Profound Peripheral Insulin Resistance, Independent of Obesity, in Polycystic Ovary SyndromeDiabetes, 1989
- Amenorrhea associated with bilateral polycystic ovariesAmerican Journal of Obstetrics and Gynecology, 1935