The Development and Psychometric Validation of the Central Sensitization Inventory
Top Cited Papers
- 27 September 2011
- journal article
- research article
- Published by Wiley in Pain Practice
- Vol. 12 (4), 276-285
- https://doi.org/10.1111/j.1533-2500.2011.00493.x
Abstract
Central sensitization (CS) has been proposed as a common pathophysiological mechanism to explain related syndromes for which no specific organic cause can be found. The term “central sensitivity syndrome (CSS)” has been proposed to describe these poorly understood disorders related to CS. The goal of this investigation was to develop the Central Sensitization Inventory (CSI), which identifies key symptoms associated with CSSs and quantifies the degree of these symptoms. The utility of the CSI, to differentiate among different types of chronic pain patients who presumably have different levels of CS impairment, was then evaluated. Study 1 demonstrated strong psychometric properties (test–retest reliability = 0.817; Cronbach’s alpha = 0.879) of the CSI in a cohort of normative subjects. A factor analysis (including both normative and chronic pain subjects) yielded 4 major factors (all related to somatic and emotional symptoms), accounting for 53.4% of the variance in the dataset. In Study 2, the CSI was administered to 4 groups: fibromyalgia (FM); chronic widespread pain without FM; work‐related regional chronic low back pain (CLBP); and normative control group. Analyses revealed that the patients with FM reported the highest CSI scores and the normative population the lowest (P < 0.05). Analyses also demonstrated that the prevalence of previously diagnosed CSSs and related disorders was highest in the FM group and lowest in the normative group (P < 0.001). Taken together, these 2 studies demonstrate the psychometric strength, clinical utility, and the initial construct validity of the CSI in evaluating CS‐related clinical symptoms in chronic pain populations. ▪Keywords
This publication has 79 references indexed in Scilit:
- Gray Matter Volumes of Pain-Related Brain Areas Are Decreased in Fibromyalgia SyndromeThe Journal of Pain, 2011
- Central Sensitivity Syndromes: Mounting Pathophysiologic Evidence to Link Fibromyalgia with Other Common Chronic Pain DisordersPain Management Nursing, 2011
- Risk Factors Predicting the Development of Widespread Pain From Chronic Back or Neck PainThe Journal of Pain, 2010
- One single diagnosis, bodily distress syndrome, succeeded to capture 10 diagnostic categories of functional somatic syndromes and somatoform disordersJournal of Psychosomatic Research, 2010
- Symptom profile of persons self-reporting whiplash: a Norwegian population-based study (HUNT 2)European Spine Journal, 2009
- Feeling Bad in More Ways than One: Comorbidity Patterns of Medically Unexplained and Psychiatric ConditionsJournal of General Internal Medicine, 2007
- Subgrouping of fibromyalgia patients on the basis of pressure‐pain thresholds and psychological factorsArthritis & Rheumatism, 2003
- The self‐administered comorbidity questionnaire: A new method to assess comorbidity for clinical and health services researchArthritis Care & Research, 2003
- The multidimensional Fatigue Inventory (MFI) psychometric qualities of an instrument to assess fatigueJournal of Psychosomatic Research, 1995
- The american college of rheumatology 1990 criteria for the classification of fibromyalgiaArthritis & Rheumatism, 1990