The role of cavitation microjets in the therapeutic applications of ultrasound
- 31 March 2004
- journal article
- Published by Elsevier BV in Japanese Journal of Clinical Oncology
- Vol. 30 (3), 381-387
- https://doi.org/10.1016/j.ultrasmedbio.2003.10.019
Abstract
The dynamics of a gas bubble situated in a sound-irradiated liquid and near a rigid boundary was studied theoretically to get a better understanding of the role of cavitation microjets in the therapeutic applications of ultrasound (US). The boundary integral method was adopted to simulate the temporal development of the bubble shape, jet formation during bubble collapse and bubble migration. It was found that the dynamic behaviour of the jet and the migratory characteristics of the bubble depend not only on the distance between bubble and boundary but, also, on the properties of the acoustic field. For frequencies of sound fields smaller than or equal to the resonance frequency of the bubble, jet formation and bubble migration toward the boundary are the main features of the interaction. No jet formation was observed for frequencies of sound fields larger than the resonance frequency of the bubble, and the bubble kept its initial position from the boundary throughout its motion. The pressure generated by the impact of the jet developed during bubble collapse close to the boundary may result in the fragmentation of brittle objects, such as renal calculi, dental tartar or intraocular lens.Keywords
Funding Information
- Japan Society for the Promotion of Science (S-02230)
This publication has 22 references indexed in Scilit:
- Transrectal High-Intensity Focused Ultrasound: Minimally Invasive Therapy of Localized Prostate CancerJournal of Endourology, 2000
- Interaction of lithotripter-generated shock waves with air bubblesThe Journal of the Acoustical Society of America, 1993
- A numerical investigation of non-spherical rebounding bubblesJournal of Fluid Mechanics, 1992
- Bifurcation structure of bubble oscillatorsThe Journal of the Acoustical Society of America, 1990
- Cavitation Bubbles Near BoundariesAnnual Review of Fluid Mechanics, 1987
- Treatment of experimental lens capsular tears with intense focused ultrasound.British Journal of Ophthalmology, 1985
- Impact of a liquid mass on a perfectly plastic solidJournal of Fluid Mechanics, 1983
- The Impact of Compressible LiquidsAnnual Review of Fluid Mechanics, 1983
- Bubble Dynamics and CavitationAnnual Review of Fluid Mechanics, 1977
- Numerical investigation of nonlinear oscillations of gas bubbles in liquidsThe Journal of the Acoustical Society of America, 1976