Degradable Magnetic Composites for Minimally Invasive Interventions: Device Fabrication, Targeted Drug Delivery, and Cytotoxicity Tests
Top Cited Papers
- 25 November 2015
- journal article
- research article
- Published by Wiley in Advanced Materials
- Vol. 28 (3), 533-538
- https://doi.org/10.1002/adma.201503112
Abstract
Superparamagnetic nanoparticles and a functional, degradable polymer matrix based on poly(ethylene glycol) are combined to enable fully degradable magnetic microdevices for minimally invasive biomedical applications. A bioinspired helical microrobot platform mimicking Escherichia coli bacteria is fabricated and actuated using weak rotating magnetic fields. Locomotion based on corkscrew propulsion, targeted drug delivery, and low‐degradation‐product cytotoxicity are demonstrated.Keywords
Funding Information
- European Research Council Starting Grant (336456)
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