Medication Adherence in Type 2 Diabetes: The ENTRED Study 2007, a French Population-Based Study
Open Access
- 5 March 2012
- journal article
- research article
- Published by Public Library of Science (PLoS) in PLOS ONE
- Vol. 7 (3), e32412
- https://doi.org/10.1371/journal.pone.0032412
Abstract
Adherence to prescribed medications is a key dimension of healthcare quality. The aim of this large population-based study was to evaluate self-reported medication adherence and to identify factors linked with poor adherence in patients with type 2 diabetes in France. The ENTRED study 2007, a French national survey of people treated for diabetes, was based on a representative sample of patients who claimed reimbursement for oral hypoglycaemic agents and/or insulin at least three times between August 2006 and July 2007, and who were randomly selected from the database of the two main National Health Insurance Systems. Medication adherence was determined using a six-item self-administered questionnaire. A multinomial polychotomous logistic regression model was used to identify factors associated with medication adherence in the 3,637 persons with type 2 diabetes. Thirty nine percent of patients reported good medication adherence, 49% medium adherence and 12% poor adherence. The factors significantly associated with poor adherence in multivariate analysis were socio-demographic factors: age 8% and existing diabetes complications; and health care-related factors: difficulties for taking medication alone, decision making by the patient only, poor acceptability of medical recommendations, lack of family or social support, need for information on treatment, reporting no confidence in the future, need for medical support and follow-up by a specialist physician. In a country with a high level of access to healthcare, our study demonstrated a substantial low level of medication adherence in type 2 diabetic patients. Better identification of those with poor adherence and individualised suitable recommendations remain essential for better healthcare management.Keywords
This publication has 44 references indexed in Scilit:
- Participatory Decision Making, Patient Activation, Medication Adherence, and Intermediate Clinical Outcomes in Type 2 Diabetes: A STARNet StudyAnnals of Family Medicine, 2010
- Factors that Affect Medication Adherence in Elderly Patients with Diabetes MellitusKorean Diabetes Journal, 2010
- The effect of an educational intervention on patients' knowledge about hypertension, beliefs about medicines, and adherenceResearch in Social and Administrative Pharmacy, 2009
- How do patients with type 2 diabetes perceive their disease? Insights from the French DIABASIS surveyDiabetes & Metabolism, 2009
- Racial differences in long-term adherence to oral antidiabetic drug therapy: a longitudinal cohort studyBMC Health Services Research, 2009
- Medication Adherence and Racial Differences in A1C ControlDiabetes Care, 2008
- Adherence to Preventive MedicationsDiabetes Care, 2006
- Adherence to MedicationNew England Journal of Medicine, 2005
- Improving Adherence to Diabetes Self-Management RecommendationsDiabetes Spectrum, 2002
- The Patient-Provider Relationship: Attachment Theory and Adherence to Treatment in DiabetesAmerican Journal of Psychiatry, 2001