Border-cell migration: the race is on
- 1 January 2003
- journal article
- review article
- Published by Springer Science and Business Media LLC in Nature Reviews Molecular Cell Biology
- Vol. 4 (1), 13-24
- https://doi.org/10.1038/nrm1006
Abstract
The conversion of stationary epithelial cells into migratory, invasive cells is important for normal embryonic development and tumour metastasis. Border-cell migration in the ovary of Drosophila melanogaster has emerged as a simple, genetically tractable model for studying this process. Three distinct signals, which are also upregulated in cancer, control border-cell migration, so identifying further genes that are involved in border-cell migration could provide new insights into tumour invasion.Keywords
This publication has 54 references indexed in Scilit:
- Myosin VI is required for E-cadherin-mediated border cell migrationNature, 2002
- Turn‐off, drop‐out: Functional state switching of cadherinsDevelopmental Dynamics, 2002
- Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complexNature, 2002
- Paracrine Signaling through the JAK/STAT Pathway Activates Invasive Behavior of Ovarian Epithelial Cells in DrosophilaCell, 2001
- N-Cadherin Extracellular Repeat 4 Mediates Epithelial to Mesenchymal Transition and Increased MotilityThe Journal of cell biology, 2000
- The Level of C/EBP Protein Is Critical for Cell Migration during Drosophila Oogenesis and Is Tightly Controlled by Regulated DegradationMolecular Cell, 2000
- The role of STATs in transcriptional control and their impact on cellular functionOncogene, 2000
- AIB1, a Steroid Receptor Coactivator Amplified in Breast and Ovarian CancerScience, 1997
- The unc-5, unc-6, and unc-40 genes guide circumferential migrations of pioneer axons and mesodermal cells on the epidermis in C. elegansNeuron, 1990
- The ecdysoneless (ecd1ts) mutation disrupts ecdysteroid synthesis autonomously in the ring gland of Drosophila melanogasterDevelopmental Biology, 1987