Implications of Reduced Callosal Area for Social Skills after Severe Traumatic Brain Injury in Children
- 1 October 2009
- journal article
- research article
- Published by Mary Ann Liebert Inc in Journal of Neurotrauma
- Vol. 26 (10), 1645-1654
- https://doi.org/10.1089/neu.2009.0916
Abstract
The corpus callosum has been shown to be particularly vulnerable to the effects of traumatic brain injury (TBI) in childhood, and severe injury frequently results in a smaller corpus callosum post-injury. However, the long-term effects of TBI on the integrity of the callosum, as well as the potential functional significance of callosal injury are poorly understood. Some studies suggest the corpus callosum may be involved in social skills, which are often reduced following TBI. In this study, callosal size was investigated in 37 individuals 10 years post–childhood TBI, and its relationship with social competence was examined. The results indicate that individuals who sustain severe TBI in childhood display reduced callosal size 10 years post-injury. In addition, callosal size correlated significantly with social skills, suggesting that callosal atrophy may be related to poorer social skills after TBI. These findings highlight the persistence of callosal abnormalities, which may be a result of interrupted neural development after childhood TBI. The results further underscore the potential importance of the corpus callosum for social competence after TBI.Keywords
This publication has 61 references indexed in Scilit:
- Arrested development and disrupted callosal microstructure following pediatric traumatic brain injury: relation to neurobehavioral outcomesNeuroImage, 2008
- Diffusion Tensor Imaging in Relation to Cognitive and Functional Outcome of Traumatic Brain Injury in ChildrenJournal of Head Trauma Rehabilitation, 2008
- Neurocognitive and neuroimaging correlates of pediatric traumatic brain injury: A diffusion tensor imaging (DTI) studyArchives of Clinical Neuropsychology, 2007
- Social outcomes in childhood brain disorder: A heuristic integration of social neuroscience and developmental psychology.Psychological Bulletin, 2007
- Self-regulation and social and behavioral functioning following childhood traumatic brain injuryJournal of the International Neuropsychological Society, 2006
- Functional Plasticity or Vulnerability After Early Brain Injury?Published by American Academy of Pediatrics (AAP) ,2005
- Gross morphology and morphometric sequelae in the hippocampus, fornix, and corpus callosum of patients with severe non-missile traumatic brain injury without macroscopically detectable lesions: a T1 weighted MRI studyJournal of Neurology, Neurosurgery & Psychiatry, 2004
- Neuropsychological and information processing deficits following mild traumatic brain injuryJournal of the International Neuropsychological Society, 2004
- Social Problem-Solving Skills in Children with Traumatic Brain Injury: Long-Term Outcomes and Prediction of Social CompetenceChild Neuropsychology, 2002
- A quantitative MRI study of the corpus callosum in children and adolescentsDevelopmental Brain Research, 1996