Calcific Aortic Stenosis and Gastrointestinal Bleeding

Abstract
To the Editor: Twenty-two years ago in this column, Dr. E. C. Heyde noted the association of calcific aortic stenosis and gastrointestinal bleeding in elderly patients.1 Confirmation of the association followed in this Journal and others.2 3 4 5 Boss and Rosenblum reported on a patient with multiple vascular lesions in the right colon that were missed on barium examination but seen at autopsy, and they suggested that the lesions were the source of bleeding.6 Such lesions, termed angiodysplasia by Galdabini,7 may be identified by angiography. We have performed aortic-valve replacement in two patients with what may be called Heyde's syndrome, with apparent . . .