Primary Intracerebral Hemorrhage Mortality Reduction After Installation of a Tap-Water Supply System in an Arseniasis-Endemic Area in Southwestern Taiwan
- 6 February 2007
- journal article
- research article
- Published by Taylor & Francis Ltd in Journal of Toxicology and Environmental Health, Part A
- Vol. 70 (6), 539-546
- https://doi.org/10.1080/15287390600870940
Abstract
Mortality and morbidity of vascular diseases, including stroke, are known to be associated with chronic exposure to inorganic arsenic through drinking water. A tap-water supply system was implemented in the early 1960s in the blackfoot disease (BFD) endemic areas of Taiwan. The objective of this study was to examine whether mortality attributed to stroke decreased among residents living in the BFD-endemic areas after the curtailment of arsenic exposure. Further it was of interest to determine whether arsenic exposure was related to a specific type of stroke. Standardized mortality ratios (SMRs) for stroke were calculated for the BFD endemic area for the years 1971–2000. The study results show that mortality due to primary intracerebral hemorrhage (PIH) declined gradually after the improvement of drinking-water supply system by elimination of arsenic exposure through removal of artesian well water. Based on the reversibility and specificity criteria, the association between arsenic exposure and mortality due to PIH is likely to be causal.Keywords
This publication has 26 references indexed in Scilit:
- Lung cancer mortality reduction after installation of tap-water supply system in an arseniasis-endemic area in Southwestern TaiwanLung Cancer, 2004
- DOES ARSENIC EXPOSURE INCREASE THE RISK FOR LIVER CANCER?1Journal of Toxicology and Environmental Health, Part A, 2004
- ISCHEMIC HEART DISEASE MORTALITY REDUCTION IN AN ARSENIASIS-ENDEMIC AREA IN SOUTHWESTERN TAIWAN AFTER A SWITCH IN THE TAP-WATER SUPPLY SYSTEMJournal of Toxicology and Environmental Health, Part A, 2004
- CANCER MORTALITY TRENDS IN A BLACKFOOT DISEASE ENDEMIC COMMUNITY OF TAIWAN FOLLOWING WATER SOURCE REPLACEMENTJournal of Toxicology and Environmental Health, Part A, 1998
- ARSENIC SPECIES IN DRINKING WATER, HAIR, FINGERNAILS, AND URINE OF PATIENTS WITH BLACKFOOT DISEASEJournal of Toxicology and Environmental Health, Part A, 1998
- SMOKING AS A RISK FACTOR FOR CEREBRAL ISCHAEMIAThe Lancet, 1989
- Diabetes and the risk of stroke. The Honolulu Heart ProgramJAMA, 1987
- Stroke and Alcohol ConsumptionThe New England Journal of Medicine, 1986
- Blood pressure course in patients with acute stroke and matched controls.Stroke, 1986
- Respiratory Cancer Among Copper Smelter Workers: Recent Mortality StatisticsJournal of Occupational and Environmental Medicine, 1981