Eosinophils, bronchial hyperreactivity and late‐phase asthmatic reactions
- 1 September 1985
- journal article
- Published by Wiley in Clinical and Experimental Allergy
- Vol. 15 (5), 411-418
- https://doi.org/10.1111/j.1365-2222.1985.tb02290.x
Abstract
We have measured airways reactivity (methacholine PC20) and blood eosinophils in eleven asthmatics with allergen-induced late-phase reactions. Before challenge there was a significant (P20. After allergen inhalation eosinophil counts were significantly (P20 (P<0.01) in the late-phase responders. These observations suggest that there may be a direct association between eosinophils and airway reactivity in subjects who develop late-phase asthmatic reactions.Keywords
This publication has 21 references indexed in Scilit:
- Effect of beclomethasone dipropionate on bronchial responsiveness to histamine in controlled nonsteroid-dependent asthmaJournal of Allergy and Clinical Immunology, 1985
- Leukocyte Activation in Allergen-Induced Late-Phase Asthmatic ReactionsNew England Journal of Medicine, 1984
- Immunologic studies in allergen-induced late-phase asthmatic reactionsJournal of Allergy and Clinical Immunology, 1984
- Bronchoalveolar lavage in asthma: The effect of disodium cromoglycate (cromolyn) on leukocyte counts, immunoglobulins, and complementJournal of Allergy and Clinical Immunology, 1984
- IDENTIFICATION BY IMMUNOFLUORESCENCE OF EOSINOPHIL GRANULE MAJOR BASIC PROTEIN IN LUNG TISSUES OF PATIENTS WITH BRONCHIAL ASTHMAThe Lancet, 1982
- Neutrophil Chemotactic Activity in Antigen-Induced Late Asthmatic ReactionsNew England Journal of Medicine, 1982
- Reproducibility and comparison of responses to inhaled histamine and methacholine.Thorax, 1978
- DIURNAL VARIATION IN THE NUMBER OF CIRCULATING EOSINOPHIL LEUCOCYTES IN NORMAL CONTROLS AND ASTHMATICSAllergy, 1977
- Late bronchial obstructive reaction to experimental inhalation of house dust extractClinical and Experimental Allergy, 1972
- A Clinical and Pathological Study of Fatal Cases of Status AsthmaticusThorax, 1953