Tailoring new enzyme functions by rational redesign
- 26 July 2000
- journal article
- review article
- Published by Elsevier BV in Current Opinion in Structural Biology
- Vol. 10 (4), 405-410
- https://doi.org/10.1016/s0959-440x(00)00106-8
Abstract
No abstract availableKeywords
This publication has 57 references indexed in Scilit:
- Conversion of an Engineered Potassium-binding Site into a Calcium-selective Site in Cytochrome c PeroxidaseJournal of Biological Chemistry, 1999
- Deletion of the four C-terminal residues of PepC converts an aminopeptidase into an oligopeptidaseProtein Engineering, Design and Selection, 1999
- Redesign of Cytochrome c Peroxidase into a Manganese Peroxidase: Role of Tryptophans in Peroxidase ActivityBiochemistry, 1999
- Probing the Kinetic Mechanism and Coenzyme Specificity of Glutathione Reductase from the Cyanobacterium Anabaena PCC 7120 by Redesign of the Pyridine-Nucleotide-Binding SiteBiochemistry, 1999
- The Effects of an Engineered Cation Site on the Structure, Activity, and EPR Properties of Cytochrome c PeroxidaseBiochemistry, 1999
- Rational Design of a Functional Metalloenzyme: Introduction of a Site for Manganese Binding and Oxidation into a Heme PeroxidaseBiochemistry, 1998
- Definition and Redesign of the Extended Substrate Specificity of Granzyme BJournal of Biological Chemistry, 1998
- Engineering the S1‘ Subsite of Trypsin: Design of a Protease Which Cleaves between Dibasic ResiduesBiochemistry, 1998
- Re-design of Saccharomyces cerevisiae flavocytochrome b2: introduction of l-mandelate dehydrogenase activityBiochemical Journal, 1998
- Redesign of soluble fatty acid desaturases from plants for altered substrate specificity and double bond positionProceedings of the National Academy of Sciences of the United States of America, 1997