Increased Radioresistance and Accelerated B Cell Lymphomas in Mice with Mdmx Mutations that Prevent Modifications by DNA-Damage-Activated Kinases
- 1 July 2009
- journal article
- research article
- Published by Elsevier BV in Cancer Cell
- Vol. 16 (1), 33-43
- https://doi.org/10.1016/j.ccr.2009.05.008
Abstract
No abstract availableThis publication has 65 references indexed in Scilit:
- Dual effect of p53 on radiation sensitivity in vivo: p53 promotes hematopoietic injury, but protects from gastro-intestinal syndrome in miceOncogene, 2004
- Accelerated MDM2 auto-degradation induced by DNA-damage kinases is required for p53 activationThe EMBO Journal, 2004
- DNA Damage-induced MDMX Degradation Is Mediated by MDM2Journal of Biological Chemistry, 2003
- Hdmx Protein Stability Is Regulated by the Ubiquitin Ligase Activity of Mdm2Journal of Biological Chemistry, 2003
- c-Myc Augments Gamma Irradiation-Induced Apoptosis by Suppressing Bcl-XLMolecular and Cellular Biology, 2003
- MDM2 Promotes Ubiquitination and Degradation of MDMXMolecular and Cellular Biology, 2003
- GermlineTP53 mutations and Li-Fraumeni syndromeHuman Mutation, 2003
- The p53–Mdm2 module and the ubiquitin systemSeminars in Cancer Biology, 2002
- DNA Damage Induces MDMX Nuclear Translocation by p53-Dependent and -Independent MechanismsMolecular and Cellular Biology, 2002
- Live or let die: the cell's response to p53Nature Reviews Cancer, 2002