Bone graft substitutes in anterior cervical discectomy and fusion
Open Access
- 17 January 2009
- journal article
- review article
- Published by Springer Science and Business Media LLC in European Spine Journal
- Vol. 18 (4), 449-464
- https://doi.org/10.1007/s00586-008-0878-4
Abstract
Anterior cervical discectomy with fusion is a common surgical procedure for patients suffering pain and/or neurological deficits and unresponsive to conservative management. For decades, autologous bone grafted from the iliac crest has been used as a substrate for cervical arthrodesis. However patient dissatisfaction with donor site morbidity has led to the search for alternative techniques. We present a literature review examining the progress of available grafting options as assessed in human clinical trials, considering allograft-based, synthetic, factor- and cell-based technologies.Keywords
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