RAS P21 Protein Activator 3 (RASA3) Specifically Promotes Pathogenic T Helper 17 Cell Generation by Repressing T-Helper-2-Cell-Biased Programs
- 1 November 2018
- journal article
- research article
- Published by Elsevier BV in Immunity
- Vol. 49 (5), 886-898.e5
- https://doi.org/10.1016/j.immuni.2018.09.004
Abstract
No abstract availableKeywords
Funding Information
- Cancer Center Core
- National Natural Science Foundation of China (81402549, LJQ2015033)
- NIH/NHLBI (HL130404)
- NIH/NIAID (AI097392, AI123193)
- National Multiple Sclerosis Society (RG-1802-30483)
- Yang Family Biomedical Scholars Award
This publication has 60 references indexed in Scilit:
- A Validated Regulatory Network for Th17 Cell SpecificationCell, 2012
- Induction and molecular signature of pathogenic TH17 cellsNature Immunology, 2012
- The many faces of Th17 cellsCurrent Opinion in Immunology, 2011
- Control of TH17 cells occurs in the small intestineNature, 2011
- The encephalitogenicity of TH17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSFNature Immunology, 2011
- Generation of pathogenic TH17 cells in the absence of TGF-β signallingNature, 2010
- Interleukin-23 Drives Intestinal Inflammation through Direct Activity on T CellsImmunity, 2010
- Critical Regulation of Early Th17 Cell Differentiation by Interleukin-1 SignalingImmunity, 2009
- The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17–producing effector T helper cells in vivoNature Immunology, 2009
- Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cellsNature, 2006