The Reduction of Mannich Bases and Their Derivatives by Tri-N-Butyltin Hydride
- 1 August 1988
- journal article
- research article
- Published by Taylor & Francis Ltd in Synthetic Communications
- Vol. 18 (11), 1207-1211
- https://doi.org/10.1080/00397918808060912
Abstract
Overall nuclear methylation of phenols was achieved by deamination of their Mannich bases and related derivatives with tri-n-butyltin hydride. The α-methylation of ketones was also similarly achieved.Keywords
This publication has 12 references indexed in Scilit:
- An Efficient Method for the Conversion of Phenolic Mannich Bases to C-Methylated Phenols. Synthesis of 3,6-DimethylcatecholSynthetic Communications, 1982
- ‘One-pot’ conversion of mannich bases via quaternary ammonium salts into the corresponding methyl compounds with sodium cyanoborohydride in hexamethylphosphoramideJournal of the Chemical Society, Chemical Communications, 1978
- Advances in the Chemistry of Mannich BasesSynthesis, 1973
- Reaction of Phenolic Mannich Base Methiodides and Oxides with Various NucleophilesJournal of the American Chemical Society, 1959
- The Preparation of Some Acenaphthoxyacetic AcidsJournal of the American Chemical Society, 1951
- 3-Pyridols in the Mannich ReactionJournal of the American Chemical Society, 1949
- The Total Synthesis of QuinineJournal of the American Chemical Society, 1945
- 143. Nuclear methylation of phenols by means of methanolic sodium methoxideJournal of the Chemical Society, 1942
- Über die Synthese von β‐Keto‐basen aus fett‐aromatischen Ketonen, Formaldehyd und sekundären AminenBerichte der deutschen chemischen Gesellschaft (A and B Series), 1922
- Synthese von β‐Ketobasen aus Acetophenon, Formaldehyd und AminsalzenBerichte der deutschen chemischen Gesellschaft (A and B Series), 1922