Inbreeding depression in livestock species: review and meta‐analysis
- 28 June 2014
- journal article
- research article
- Published by Wiley in Animal Genetics
- Vol. 45 (5), 618-628
- https://doi.org/10.1111/age.12178
Abstract
Inbreeding, by virtue of its consequence on traits of interest, is a topic of major interest for geneticists and animal breeders. Based on meta-analysis conducted on 57 studies and seven livestock species considering a wide variety of selected traits, it was estimated that inbreeding depression corresponds to on average a decrease of 0.137 percent of the mean of a trait per 1 percent of inbreeding. The decrease was larger for production traits (reduction of 0.351%) than for other trait categories. For populations raised as purebreds, inbreeding depression may impact the economic income of breeders. There is a need for studies assessing the existence of an inbreeding purge phenomenon as well as the impact of inbreeding on adaptation capacities of livestock species. Promises brought by the development of dense genotyping as well as functional genomics will increase the capacities to improve our understanding and management of the phenomenonKeywords
This publication has 76 references indexed in Scilit:
- Detection of Haplotypes Associated with Prenatal Death in Dairy Cattle and Identification of Deleterious Mutations in GART, SHBG and SLC37A2PLOS ONE, 2013
- Genomic selection of purebred animals for crossbred performance in the presence of dominant gene actionGenetics Selection Evolution, 2013
- Methods to estimate effective population size using pedigree data: Examples in dog, sheep, cattle and horseGenetics Selection Evolution, 2013
- Runs of homozygosity and population history in cattleBMC Genomic Data, 2012
- Pedigree analysis and inbreeding depression on growth traits in Brazilian Marchigiana and Bonsmara breeds1Journal of Animal Science, 2012
- An ABC estimate of pedigree error rate: application in dog, sheep and cattle breedsAnimal Genetics, 2011
- Quantification of Inbreeding Due to Distant Ancestors and Its Detection Using Dense Single Nucleotide Polymorphism DataGenetics, 2011
- Invited review: Genomic selection in dairy cattle: Progress and challengesJournal of Dairy Science, 2009
- Purging of inbreeding depression within the Irish Holstein-Friesian populationGenetics Selection Evolution, 2009
- Analyses of lamb weight and ewe litter size in various lines of Spanish Merino sheepSmall Ruminant Research, 1998