The feasibility of using a shorter version of the Profile of Mood States is examined. Eighty-three cancer patients were administered the Profile of Mood States. The scales' internal consistency (coefficient alpha) and the items' face validity were used as criteria for eliminating items. The number of items was reduced from 65 to 37 and the correlation coefficients between the short and original scales were all above .95, indicating the suitability of the short version for estimating the original mood scale scores in this population.