Participation in screening colonoscopy in first-degree relatives from patients with colorectal cancer
Open Access
- 1 September 2007
- journal article
- research article
- Published by Elsevier BV in Annals Of Oncology
- Vol. 18 (9), 1518-1522
- https://doi.org/10.1093/annonc/mdm200
Abstract
Background: Current guidelines recommend screening colonoscopy in first-degree relatives of patients with colon cancer. The aim of this state-wide study was to investigate the compliance for colonoscopic in first-degree relatives, who were younger than 60 years of age. Methods: A total of 602 patients were identified from the tumor registry of the public health insurance of Lower Saxony. A questionnaire was sent to these patients, which included a number of different questions regarding their knowledge about the risk of colon cancer for their family members, as well as their participation in screening colonoscopy. Results: Data from 442 patients and their first-degree relatives (1005 siblings and 354 parents) were available; 178 parents had undergone screening colonoscopy and 344 siblings. Interestingly, the percentage of siblings who underwent screening colonoscopy was significantly higher (27%) among those siblings where the index patients were aware of the increased risk for the first-degree relatives, in contrast to the siblings of the index patients who were not aware of this risk (20%). Conclusion: This study demonstrates that only a minority of first-degree relatives undergo screening colonoscopy and that informing patients about the potential risk for their relatives will increase participation in screening colonoscopy in first-degree relatives of the patients.Keywords
This publication has 22 references indexed in Scilit:
- Colonoscopy in Colorectal-Cancer Screening for Detection of Advanced NeoplasiaNew England Journal of Medicine, 2006
- Low compliance with colonoscopic screening in first‐degree relatives of patients with large adenomasAlimentary Pharmacology & Therapeutics, 2006
- Colorectal cancer (CRC) screening using sigmoidoscopy followed by colonoscopy: a feasibility and efficacy study on a cancer institute based populationAnnals Of Oncology, 2006
- Relatives of colorectal cancer patients: Factors associated with screening behaviorAmerican Journal of Preventive Medicine, 2003
- Colorectal cancer screening and surveillance: Clinical guidelines and rationale—Update based on new evidenceGastroenterology, 2003
- Colonoscopic screening in first-degree relatives of patients with ‘sporadic’ colorectal cancer: A case-control studyGastroenterology, 1998
- Results of a pilot study of endoscopic screening of first degree relatives of colorectal cancer patients in Italy.Journal of Epidemiology and Community Health, 1997
- Colonoscopic Screening Examination of Relatives of Patients with Colorectal Cancer:I. A Comparison with an Endoscopically Screened Normal PopulationScandinavian Journal of Gastroenterology, 1992
- How prevalent is cancer family syndrome?Gut, 1991
- Cancer incidence among parents of patients with colorectal cancerInternational Journal of Cancer, 1991