Slide‐based cytometry for cytomics—A minireview
Open Access
- 28 June 2006
- journal article
- review article
- Published by Wiley in Cytometry Part A
- Vol. 69A (7), 555-562
- https://doi.org/10.1002/cyto.a.20317
Abstract
In the postgenomic era, to gain the most detailed quantitative data from biological specimens has become increasingly important in the emerging new fields of high‐content and high‐throughput single‐cell analysis for systems biology and cytomics. Areas of research and diagnosis with the demand to virtually measure “anything” in the cell include immunophenotyping, rare cell detection and characterization in the case of stem cells and residual tumor cells, tissue analysis, and drug discovery. Systemic analysis is also a prerequisite for predictive medicine by genomics, proteomics, and cytomics. This issue of Cytometry Part A is dedicated to innovative concepts of system wide single cells analysis and manipulation, new technologies, data analysis and display, and, finally, quality assessment. The manuscripts to these chapters are provided by cutting edge experts in the fields. This overview will briefly highlight the most important aspects of this continuously developing field. © 2006 International Society for Analytical CytologyKeywords
This publication has 69 references indexed in Scilit:
- Automated interpretation of subcellular patterns in fluorescence microscope images for location proteomicsCytometry Part A, 2006
- Cytomics, the human cytome project and systems biology: top‐down resolution of the molecular biocomplexity of organisms by single cell analysisCell Proliferation, 2005
- Neuronal Differentiation of P19 Embryonal Carcinoma Cells Modulates Kinin B2 Receptor Gene Expression and FunctionJournal of Biological Chemistry, 2005
- Systems Biology and New Technologies Enable Predictive and Preventative MedicineScience, 2004
- Data pattern analysis for the individualised pretherapeutic identification of high-risk diffuse large B-cell lymphoma (DLBCL) patients by cytomicsCytometry, 2004
- Extra‐cellular matrix in vascular networksCell Proliferation, 2004
- A Modular, Fully Integrated Ultra-High-Throughput Screening System Based on Confocal Fluorescence Analysis TechniquesSLAS Discovery, 2003
- Invention and commercialization in optical bioimagingNature Biotechnology, 2003
- Caffeine dissociates complexes between DNA and intercalating dyes: Application for bleaching fluorochrome-stained cells for their subsequent restaining and analysis by laser scanning cytometryCytometry, 2000
- High affinity binding of fluorescein isothiocyanate to eosinophils detected by laser scanning cytometry: A potential source of error in analysis of blood samples utilizing fluorescein-conjugated reagents in flow cytometryCytometry, 1999