Phosphorylation by Casein Kinase I Promotes the Turnover of the Mdm2 Oncoprotein via the SCFβ-TRCP Ubiquitin Ligase
- 17 August 2010
- journal article
- research article
- Published by Elsevier BV in Cancer Cell
- Vol. 18 (2), 147-159
- https://doi.org/10.1016/j.ccr.2010.06.015
Abstract
No abstract availableThis publication has 59 references indexed in Scilit:
- Control of Cyclin D1 and Breast Tumorigenesis by the EglN2 Prolyl HydroxylaseCancer Cell, 2009
- Deregulated proteolysis by the F-box proteins SKP2 and β-TrCP: tipping the scales of cancerNature Reviews Cancer, 2008
- Recurrent Initiation: A Mechanism for Triggering p53 Pulses in Response to DNA DamageMolecular Cell, 2008
- Phosphorylation of CK1δ: identification of Ser370 as the major phosphorylation site targeted by PKA in vitro and in vivoBiochemical Journal, 2007
- Degradation of Mcl-1 by β-TrCP Mediates Glycogen Synthase Kinase 3-Induced Tumor Suppression and ChemosensitizationMolecular and Cellular Biology, 2007
- Sonic hedgehog Signaling Regulates Gli2 Transcriptional Activity by Suppressing Its Processing and DegradationMolecular and Cellular Biology, 2006
- Function and regulation of cullin–RING ubiquitin ligasesNature Reviews Molecular Cell Biology, 2005
- Structure of a β-TrCP1-Skp1-β-Catenin Complex: Destruction Motif Binding and Lysine Specificity of the SCFβ-TrCP1 Ubiquitin LigaseMolecular Cell, 2003
- Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replicationNature, 2001
- Mdm2 promotes the rapid degradation of p53Nature, 1997