Robotically Assisted Sonic Therapy (RAST) for Noninvasive Hepatic Ablation in a Porcine Model: Mitigation of Body Wall Damage with a Modified Pulse Sequence
- 30 April 2019
- journal article
- research article
- Published by Springer Science and Business Media LLC in CardioVascular and Interventional Radiology
- Vol. 42 (7), 1016-1023
- https://doi.org/10.1007/s00270-019-02215-8
Abstract
Robotically assisted sonic therapy (RAST) is a nonthermal, noninvasive ablation method based on histotripsy. Prior animal studies have demonstrated the ability to create hepatic ablation zones at the focal point of an ultrasound therapy transducer; however, these treatments resulted in thermal damage to the body wall within the path of ultrasound energy delivery. The purpose of this study was to evaluate the efficacy and safety of a pulse sequence intended to mitigate prefocal body wall injury.Keywords
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