Antagonistic Effect of the Matricellular Signaling Protein CCN3 on TGF-β- and Wnt-Mediated Fibrillinogenesis in Systemic Sclerosis and Marfan Syndrome
- 1 June 2010
- journal article
- Published by Elsevier BV in Journal of Investigative Dermatology
- Vol. 130 (6), 1514-1523
- https://doi.org/10.1038/jid.2010.15
Abstract
No abstract availableKeywords
This publication has 32 references indexed in Scilit:
- CCN3 (NOV) Is a Negative Regulator of CCN2 (CTGF) and a Novel Endogenous Inhibitor of the Fibrotic Pathway in an in Vitro Model of Renal DiseaseThe American Journal of Pathology, 2009
- Molecular Subsets in the Gene Expression Signatures of Scleroderma SkinPLOS ONE, 2008
- The gene expression profile induced by Wnt 3a in NIH 3T3 fibroblastsJournal of Cell Communication and Signaling, 2007
- Smad4 cooperates with lymphoid enhancer-binding factor 1/T cell-specific factor to increase c- myc expression in the absence of TGF-β signalingProceedings of the National Academy of Sciences of the United States of America, 2006
- Wnt and TGF-β signaling are required for the induction of an in vitro model of primitive streak formation using embryonic stem cellsProceedings of the National Academy of Sciences of the United States of America, 2006
- Fibrillin in Marfan syndrome and tight skin mice provides new insights into transforming growth factor-β regulation and systemic sclerosisCurrent Opinion in Rheumatology, 2006
- Gene profiling of scleroderma skin reveals robust signatures of disease that are imperfectly reflected in the transcript profiles of explanted fibroblastsArthritis & Rheumatism, 2006
- Fibulin-2 and Fibulin-5 Alterations in Tsk Mice Associated with Disorganized Hypodermal Elastic Fibers and Skin TetheringJournal of Investigative Dermatology, 2004
- Smad-dependent and Smad-independent pathways in TGF-β family signallingNature, 2003
- Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT MethodMethods, 2001