α-Lactalbumin-enriched and probiotic-supplemented infant formula in infants with colic: growth and gastrointestinal tolerance
- 2 June 2010
- journal article
- research article
- Published by Springer Science and Business Media LLC in European Journal of Clinical Nutrition
- Vol. 64 (7), 765-767
- https://doi.org/10.1038/ejcn.2010.81
Abstract
Studies undertaken with α-lactalbumin-enriched formulae never addressed infants with colic. This study evaluated the nutritional adequacy, the gastrointestinal tolerance and the effect on colic of an α-lactalbumin-enriched and probiotic-supplemented formula. A double-blind, placebo-controlled study enrolled 66 healthy infants with colic, aged 3 weeks to 3 months, fed during 1 month with the either experimental formula (EF, Modilac Digest 1) or control formula (CF) and evaluated for efficacy and safety parameters at days 15 and 30. Weight and height gains were identical in the two groups and complied with standards (1023.4±360.4 g (EF) and 1047.4±372.1 g (CF), NS; 4.2±1.4 cm (EF) and 4.3±1.9 cm (CF), NS). No differences were found between groups for crying duration. ‘Feeding-related’ gastrointestinal side effects were significantly lower with EF than with CF (P=0.011). An α-lactalbumin-enriched and probiotic-supplemented formula guaranteed good weight and length gains to infants with colic and seemed to provide good gastrointestinal tolerance.Keywords
This publication has 9 references indexed in Scilit:
- Management of Infantile Colic: A ReviewClinical Pediatrics, 2008
- Focus on infantile colicActa Paediatrica, 2007
- α-Lactalbumin-rich infant formula fed to healthy term infants in a multicenter study: plasma essential amino acids and gastrointestinal toleranceEuropean Journal of Clinical Nutrition, 2007
- Lactobacillus reuteri(American Type Culture Collection Strain 55730) Versus Simethicone in the Treatment of Infantile Colic: A Prospective Randomized StudyPEDIATRICS, 2007
- Reduction of crying episodes owing to infantile colic: a randomized controlled study on the efficacy of a new infant formulaEuropean Journal of Clinical Nutrition, 2006
- The First Prebiotics in HumansJournal of Clinical Gastroenterology, 2004
- Growth and Safety in Term Infants Fed Reduced-Protein Formula with Added Bovine Alpha-LactalbuminJournal of Pediatric Gastroenterology and Nutrition, 2004
- “A Future of Sustainable Development Begins with Safeguarding the Health of Every Child.”Food and Nutrition Bulletin, 2004
- α‐Lactalbumin‐enriched low‐protein infant formulas: a comparison to breast milk feedingActa Paediatrica, 1996