Hepatitis C Virus Cryoglobulinemia and non-Hodgkin Lymphoma
Open Access
- 1 February 2012
- journal article
- Published by Briefland in Hepatitis Monthly
- Vol. 2012 (Volume 12,), 85-91
- https://doi.org/10.5812/hepatmon.818
Abstract
On the strength of epidemiological data,biological studies, and clinical findings, hepatitis C virus appears to be involved in the pathogenesis of a proportion of patients with non-Hodgkin lymphoma and cryoglobulinemia. The aim of this paper is to review the published literature focused on the current knowledge concerning hepatitis C virus and its potential role in the production of non-Hodgkin lymphoma and cryoglobulinemia in susceptible individuals. In this review, databases such as pubMed, embase, ISI, and Iranian databases including Iranmedex, and SID were searched. The results of this review indicate that HCV infection may be a likely cause of various B cell dysregulation disorders such as non-Hodgkin lymphoma and cryoglobulinemia. Based on current findings, it has been hypothesized that NHL and cryoglobulinemia in HCV infection may have an immune-mediated pathogenesis. In HCV infected patients, we showed an elevated risk of these two diseases. These finding suggested a possible role for chronic hepatitis C in the pathogenesis of NHL and cryoglobulinemia.Keywords
This publication has 96 references indexed in Scilit:
- HCV Infection and B-Cell LymphomagenesisAdvances in Hematology, 2011
- HLA DR-DQ combination associated with the increased risk of developing human HCV positive non-Hodgkin's lymphoma is related to the type II mixed cryoglobulinemiaTissue Antigens, 2010
- Role of the Receptor for the Globular Domain of C1q Protein in the Pathogenesis of Hepatitis C Virus-Related Cryoglobulin Vascular DamagePublished by The American Association of Immunologists ,2009
- Hepatitis C virus–induced cryoglobulinemiaKidney International, 2009
- Hepatitis C virus association with peripheral blood B lymphocytes potentiates viral infection of liver-derived hepatoma cellsBlood, 2009
- Hepatitis C virus lymphotropism and peculiar immunological phenotype: Effects on natural history and antiviral therapyWorld Journal of Gastroenterology, 2009
- Classification of lymphoid neoplasms: the microscope as a tool for disease discoveryBlood, 2008
- Mixed cryoglobulinemiaOrphanet Journal of Rare Diseases, 2008
- Predominance of type 1 (Th1) cytokine production in the liver of patients with HCV-associated mixed cryoglobulinemia vasculitisJournal of Hepatology, 2004
- Extrahepatic manifestations of hepatitis C among United States male veteransHepatology, 2002