A Chemical Reporter Strategy to Probe Glycoprotein Fucosylation
- 23 August 2006
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of the American Chemical Society
- Vol. 128 (37), 12078-12079
- https://doi.org/10.1021/ja064619y
Abstract
Fucosylated glycoproteins are involved in many cell−cell recognition events and are markers of embryonic and malignant tissue. Here we report a method for rapid profiling of fucosylated glycoproteins from human cells using 6-azido fucose as a metabolic label.This publication has 16 references indexed in Scilit:
- The sweet and sour of cancer: glycans as novel therapeutic targetsNature Reviews Cancer, 2005
- Chemistry in living systemsNature Chemical Biology, 2005
- Chemical remodelling of cell surfaces in living animalsNature, 2004
- Polytriazoles as Copper(I)-Stabilizing Ligands in CatalysisOrganic Letters, 2004
- Profiling Enzyme Activities In Vivo Using Click Chemistry MethodsCell Chemical Biology, 2004
- Ligands for L-Selectin: Homing, Inflammation, and BeyondAnnual Review of Immunology, 2004
- Protein O -fucosyltransferase 1 is an essential component of Notch signaling pathwaysProceedings of the National Academy of Sciences of the United States of America, 2003
- Fucose: biosynthesis and biological function in mammalsGlycobiology, 2003
- On the frequency of protein glycosylation, as deduced from analysis of the SWISS-PROT databaseBiochimica et Biophysica Acta (BBA) - General Subjects, 1999
- Synthesis and biological activities of three sulfated sialyl Lex ganglioside analogues for clarifying the real carbohydrate ligand structure of L-selectinBioorganic & Medicinal Chemistry, 1996