ADVANCED RETINOBLASTOMA IN MALAYSIAN CHILDREN

Abstract

Twenty children with retinoblastoma are reviewed who were treated at the University Hospital, Kuala Lumpur over 10 yr. They constitute 6.6% of childhood malignancies and all presented with advanced disease. Hereditary cases were notably absent in the the series probably because past cases have almost invariably succumbed without an opportunity to transmit the gene. With enucleation and radiotherapy 6 patients survived for 2-12 yr. The addition of vincristine and cyclophosphamide was not associated with improved survival.