The Impact of Obesity on Urine Composition and Nephrolithiasis Management
- 1 March 2013
- journal article
- research article
- Published by Mary Ann Liebert Inc in Journal of Endourology
- Vol. 27 (3), 379-383
- https://doi.org/10.1089/end.2012.0275
Abstract
Background and Purpose: Several studies have reported that obese patients have a higher risk of nephrolithiasis. The purpose of this study is to investigate the effect of overweight (OW) and obesity on stone composition, type of treatment, and urine composition. Methods: With Institutional Review Board approval, charts of adult patients who attended our dedicated stone clinic over a 5-year period starting January 2006 were reviewed. Patients were categorized into normal (body mass index 18.5–24.9), OW (25–29.9), and obese (≥30). We excluded those who did not have at least one 24-hour urine analysis. Results: OW and obese patients were more likely to have previous stones, more chance to have uric acid stones, and to be treated with shockwave lithotripsy in the community, and with ureteroscopy or percutaneous nephrolithotripsy in our center. They needed more thiazide diuretics, allopurinol, and dietitian counseling. They had statistically significant (PConclusion: OW and obese patients have different stone composition with increased excretion of stone promoters in the urine. Stone prevention measures should be introduced during metabolic syndrome evaluation.Keywords
This publication has 20 references indexed in Scilit:
- Effect of Skin-to-Stone Distance on Shockwave Lithotripsy SuccessJournal of Endourology, 2008
- Nutritional strategies in the prevention and treatment of metabolic syndromeApplied Physiology, Nutrition, and Metabolism, 2007
- Physical activity in prevention and treatment of the metabolic syndromeApplied Physiology, Nutrition, and Metabolism, 2007
- Body Size and 24-Hour Urine CompositionAmerican Journal of Kidney Diseases, 2006
- Prevalence of Overweight and Obesity in the United States, 1999-2004JAMA, 2006
- METABOLIC RISK FACTORS AND THE IMPACT OF MEDICAL THERAPY ON THE MANAGEMENT OF NEPHROLITHIASIS IN OBESE PATIENTSJournal of Urology, 2004
- Association of urinary pH with body weight in nephrolithiasisKidney International, 2004
- Time trends in reported prevalence of kidney stones in the United States: 1976–199411.See Editorial by Goldfarb, p. 1951.Kidney International, 2003
- Renal stone epidemiology: A 25-year study in Rochester, MinnesotaKidney International, 1979
- UrolithiasisScandinavian Journal of Urology and Nephrology, 1976