Insect immunity
Open Access
- 1 January 1988
- journal article
- research article
- Published by Wiley in European Journal of Biochemistry
- Vol. 171 (1-2), 17-22
- https://doi.org/10.1111/j.1432-1033.1988.tb13752.x
Abstract
Injury or injection of live bacteria into third instar larvae of the dipteran insect Phormia terranovae results in the appearance in the haemolymph of at least five groups of heat-stable, more or less basic peptides with antibacterial activity against Escherichia coli. Three of these peptides have been purified. The amino acid sequence has been completely established for one of these and partially (first 40 residues from the N-terminus) for the two others. The sequences show marked homologies indicating that the three peptides belong to a common family. They are not related to other known antibacterial peptides from insects [lysozymes, cecropins (including sarcotoxin I) and attacins]. We propose the name of diptericins for this new family of antibiotic molecules.This publication has 16 references indexed in Scilit:
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