Design and synthesis of anti-breast cancer agents from 4-piperazinylquinoline: A hybrid pharmacophore approach
- 1 February 2010
- journal article
- Published by Elsevier BV in Bioorganic & Medicinal Chemistry
- Vol. 18 (4), 1563-1572
- https://doi.org/10.1016/j.bmc.2010.01.001
Abstract
No abstract availableKeywords
This publication has 22 references indexed in Scilit:
- A 4-aminoquinoline derivative that markedly sensitizes tumor cell killing by Akt inhibitors with a minimum cytotoxicity to non-cancer cellsEuropean Journal of Medicinal Chemistry, 2010
- Recent developments in the design and synthesis of hybrid molecules basedon aminoquinoline ring and their antiplasmodial evaluationEuropean Journal of Medicinal Chemistry, 2009
- Synthesis, Activity, and Pharmacophore Development for Isatin-β-thiosemicarbazones with Selective Activity toward Multidrug-Resistant CellsJournal of Medicinal Chemistry, 2009
- The efficacy and selectivity of tumor cell killing by Akt inhibitors are substantially increased by chloroquineBioorganic & Medicinal Chemistry, 2008
- Hybrid molecules of estrone: New compounds with potential antibacterial, antifungal, and antiproliferative activitiesBioorganic & Medicinal Chemistry, 2007
- Sulforhodamine B colorimetric assay for cytotoxicity screeningNature Protocols, 2006
- Targeting multidrug resistance in cancerNature Reviews Drug Discovery, 2006
- Multicomponent therapeutics for networked systemsNature Reviews Drug Discovery, 2005
- Structure–activity relationship in the oxazolidinone–quinolone hybrid series: influence of the central spacer on the antibacterial activity and the mode of actionBioorganic & Medicinal Chemistry Letters, 2003
- New Colorimetric Cytotoxicity Assay for Anticancer-Drug ScreeningJNCI Journal of the National Cancer Institute, 1990