The ever-increasing complexities of the exon junction complex
- 17 April 2004
- journal article
- review article
- Published by Elsevier BV in Current Opinion in Cell Biology
- Vol. 16 (3), 279-284
- https://doi.org/10.1016/j.ceb.2004.03.012
Abstract
Over the past decade many studies have revealed a complex web of interconnections between the numerous steps required for eukaryotic gene expression. One set of interconnections link nuclear pre-mRNA splicing and the subsequent metabolism of the spliced mRNAs. It is now apparent that the means of connection is a set of proteins, collectively called the exon junction complex, which are deposited as a consequence of splicing upstream of mRNA exon–exon junctions.Keywords
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