Pulmonary Candidiasis in Patients with Cancer: An Autopsy Study
Open Access
- 1 February 2002
- journal article
- Published by Oxford University Press (OUP) in Clinical Infectious Diseases
- Vol. 34 (3), 400-403
- https://doi.org/10.1086/338404
Abstract
For patients who had cancer and autopsy-proven pneumonia, we evaluated whether cultures of respiratory secretions (sputum and/or bronchoalveolar lavage) performed ⩽4 weeks before autopsy were a reliable basis for the diagnosis of pulmonary candidiasis. Pulmonary candidiasis was identified at autopsy in 36 patients, but common clinical predictors were insensitive for this diagnosis. For sputum culture, the sensitivity, specificity, and the positive and negative predictive values were 85%, 60%, 42%, and 93%, respectively; for bronchoalveolar lavage culture, these values were 71%, 57%, 29%, and 89%, respectively.This publication has 7 references indexed in Scilit:
- The Role of Candida sp Isolated From Bronchoscopic Samples in Nonneutropenic PatientsSocial psychiatry. Sozialpsychiatrie. Psychiatrie sociale, 1998
- Significance of the Isolation of Candida Species from Respiratory Samples in Critically Ill, Non-neutropenic PatientsAmerican Journal of Respiratory and Critical Care Medicine, 1997
- Trends in the postmortem epidemiology of invasive fungal infections at a University HospitalJournal of Infection, 1996
- Primary Candida PneumoniaMedicine, 1993
- Fungal infections in cancer patients: An international autopsy surveyEuropean Journal of Clinical Microbiology & Infectious Diseases, 1992
- Bronchoalveolar Lavage in the Diagnosis of Pulmonary Infiltrates in Patients with Acute LeukemiaSocial psychiatry. Sozialpsychiatrie. Psychiatrie sociale, 1988
- Pulmonary disease caused by Candida speciesThe American Journal of Medicine, 1977