Hippocampal volume and declarative memory function in combat-related PTSD
- 1 November 2009
- journal article
- symposia
- Published by Cambridge University Press (CUP) in Journal of the International Neuropsychological Society
- Vol. 15 (6), 830-839
- https://doi.org/10.1017/s1355617709990476
Abstract
The proposition that declarative memory deficits are systematically related to smaller hippocampal volume was tested in a relatively large sample (n = 95) of U.S. military veterans with and without combat-related posttraumatic stress disorder. This correlative analysis was extended by including multiple measures of verbal and visual declarative memory and multiple memory-relevant regional brain volumes that had been shown to exhibit main effects of PTSD in prior work. Small-to-moderate effects were observed on verbal declarative memory in line with a recent meta-analysis; nevertheless, little or no evidence of systematic linear covariation between memory measures and brain volumes was observed. (JINS, 2009, 15, 830–839.)Keywords
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