Nitrofuran antibiotic metabolites detected at parts per million concentrations in retina of pigs—a new matrix for enhanced monitoring of nitrofuran abuse
- 22 February 2005
- journal article
- Published by Royal Society of Chemistry (RSC) in The Analyst
- Vol. 130 (4), 466-468
- https://doi.org/10.1039/b418374f
Abstract
Nitrofuran metabolite residues AOZ, AMOZ, AHD and SEM were detected at parts per million concentrations in retina of pigs fed therapeutic doses of nitrofuran antibiotics. Discovery of this residue depot may allow widespread technology transfer to laboratories lacking LC-MS/MS thus improving global monitoring of these drugs.Keywords
This publication has 7 references indexed in Scilit:
- Binding of ractopamine HCl to ocular tissues of cattle and turkeys in vivo and to melanin in vitro1,2Journal of Animal Science, 2002
- Determination of the metabolites of nitrofuran antibiotics in animal tissue by high-performance liquid chromatography–tandem mass spectrometryJournal of Chromatography A, 2001
- Determination of the furazolidone metabolite, 3-amino-2-oxazolidinone, in porcine tissues using liquid chromatography-thermospray mass spectrometry and the occurrence of residues in pigs produced in Northern IrelandJournal of Chromatography B: Biomedical Sciences and Applications, 1997
- Tissue distribution and residues of clenbuterol, salbutamol, and terbutaline in tissues of treated broiler chickensJournal of Animal Science, 1994
- Depletion of protein‐bound furazolidone metabolites containing the 3‐amino‐2‐oxazolidinone side‐chain from liver, kidney and muscle tissues from pigsFood Additives & Contaminants, 1992
- Drug Disposition in the Mammalian Eye and Brain: A Comparison of MechanismsDrug Metabolism Reviews, 1991
- The Melanin Binding of Drugs and Its ImplicationsDrug Metabolism Reviews, 1984