Determination of anaerobic threshold for assessment of functional state in patients with chronic heart failure.
- 1 August 1983
- journal article
- abstracts
- Published by Ovid Technologies (Wolters Kluwer Health) in Circulation
- Vol. 68 (2), 360-367
- https://doi.org/10.1161/01.cir.68.2.360
Abstract
The use of anaerobic threshold in assessment of aerobic capacity was evaluated in 34 normal subjects and 47 patients with various kinds of chronic heart disease. Anaerobic threshold was determined as the oxygen consumption (VO2) at which a linear relationship between pulmonary ventilation (VE) and VO2 was lost during progressive treadmill exercise. Anaerobic threshold determined in this manner was validated with that determined by blood lactate measurements in eight normal subjects and nine cardiac patients (r = .962, p less than .001). Thereafter, anaerobic threshold was determined only by respiratory measurements. In symptom-limited, maximal exercise, anaerobic threshold was reached well before maximal effort and corresponded to 70% of maximal VO2 both in normal subjects and cardiac patients. Anaerobic threshold decreased as age progressed in normal subjects (r = - .70, p less than .001). Anaerobic threshold in cardiac patients was lower than that in the normal subjects and decreased progressively as New York Heart Association functional classification advanced (normal, 32.95 +/- 6.17 ml/min/kg; class I, 22.78 +/- 3.74; class II, 16.99 +/- 3.66; class III, 12.97 +/- 2.76; p less than .01 between each group other than between class II and class III). Anaerobic threshold in cardiac patients correlated poorly with other objective indices, e.g., cardiomegaly (r = -.54, p less than .001) and rise in pulmonary wedge pressure (r = -.64, p less than .001). At anaerobic threshold, cardiac patients subjectively graded the work load as light (13%), light-to-moderate (27%), moderate (30%), and moderate-to-heavy (28%). Thus determination of anaerobic threshold by respiratory measurements is a safe, accurate, and objective method to measure aerobic capacity in cardiac patients and in normal subjects.This publication has 13 references indexed in Scilit:
- Functional capacity of patients with chronic left ventricular failure: Relationship of bicycle exercise performance to clinical and hemodynamic characterizationAmerican Journal Of Medicine, 1979
- A Respirometer for Use in the Field for the Measurement of Oxygen Consumption. ‘ The Miser ’, a Miniature, Indicating and Sampling Electronic RespirometerErgonomics, 1978
- Anaerobic threshold and maximal aerobic power for three modes of exerciseJournal of Applied Physiology, 1976
- A Comparison of the Reproducibility and Physiologic Response to Three Maximal Treadmill Exercise ProtocolsSocial psychiatry. Sozialpsychiatrie. Psychiatrie sociale, 1974
- Anaerobic threshold and respiratory gas exchange during exercise.Journal of Applied Physiology, 1973
- Maximal oxygen intake and nomographic assessment of functional aerobic impairment in cardiovascular diseaseAmerican Heart Journal, 1973
- Treadmill exercise in assessment of the functional capacity of patients with cardiac diseaseThe American Journal of Cardiology, 1972
- Functional classification of cardiac disease: A critiqueThe American Journal of Cardiology, 1972
- Work capacity determinants and physiologic cost of weight-supported work in obesityJournal of Applied Physiology, 1966
- Detecting the threshold of anaerobic metabolism in cardiac patients during exerciseThe American Journal of Cardiology, 1964