The p85β regulatory subunit of PI3K serves as a substrate for PTEN protein phosphatase activity during insulin mediated signaling
- 2 July 2010
- journal article
- research article
- Published by Elsevier BV in Biochemical and Biophysical Research Communications
- Vol. 397 (3), 513-519
- https://doi.org/10.1016/j.bbrc.2010.05.146
Abstract
No abstract availableKeywords
This publication has 37 references indexed in Scilit:
- p85 Associates with Unphosphorylated PTEN and the PTEN-Associated ComplexMolecular and Cellular Biology, 2009
- PIK3CA Mutations and PTEN Loss Correlate with Similar Prognostic Factors and Are Not Mutually Exclusive in Breast CancerClinical Cancer Research, 2007
- The p85 regulatory subunit of phosphoinositide 3-kinase down-regulates IRS-1 signaling via the formation of a sequestration complexThe Journal of cell biology, 2005
- Potential role of PTEN phosphatase in ethanol-impaired survival signaling in the liverHepatology, 2003
- The p85 Regulatory Subunit Controls Sequential Activation of Phosphoinositide 3-Kinase by Tyr Kinases and RasPublished by Elsevier BV ,2002
- Crystal Structure of the PTEN Tumor SuppressorCell, 1999
- Inhibition of Cell Migration, Spreading, and Focal Adhesions by Tumor Suppressor PTENScience, 1998
- Germline mutations in the PTEN/MMAC1 gene in patients with Cowden diseaseHuman Molecular Genetics, 1997
- Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancersNature Genetics, 1997
- PTEN , a Putative Protein Tyrosine Phosphatase Gene Mutated in Human Brain, Breast, and Prostate CancerScience, 1997