Bone mineral status in growth hormone deficiency
- 31 March 1980
- journal article
- Published by Elsevier BV in The Journal of Pediatrics
- Vol. 96 (3), 393-396
- https://doi.org/10.1016/s0022-3476(80)80679-2
Abstract
Bone mineral status was monitored by photon absorptiometry in 18 children with growth hormone deficiency. Before exogenous growth hormone therapy, bone mineral content, bone width, and BMC/BW were below predicted values. Delayed maturation, as assessed by skeletal age, accounted for approximately 35% of the deficit for these values. Height velocity doubled during therapy, and BMC, BW, and BMC/BW increased commensurate with height and weight increases so that the relative deficit was unchanged. The pathogenesis of relative osteopenia in growth hormone deficiency was not determined.Keywords
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