Comparative Analysis of African Swine Fever Virus Genotypes and Serogroups
Open Access
- 1 February 2015
- journal article
- Published by Centers for Disease Control and Prevention (CDC) in Emerging Infectious Diseases
- Vol. 21 (2), 312-315
- https://doi.org/10.3201/eid2102.140649
Abstract
African swine fever virus (ASFV) causes highly lethal hemorrhagic disease among pigs, and ASFV’s extreme antigenic diversity hinders vaccine development. We show that p72 ASFV phylogenetic analysis does not accurately define ASFV hemadsorption inhibition assay serogroups. Thus, conventional ASFV genotyping cannot discriminate between viruses of different virulence or predict efficacy of a specific ASFV vaccine.Keywords
This publication has 11 references indexed in Scilit:
- Identification and utility of innate immune system evasion mechanisms of ASFVVirus Research, 2013
- Pathogenesis of African swine fever in domestic pigs and European wild boarVirus Research, 2013
- Prospects for Development of African Swine Fever Virus VaccinesDevelopments in biologicals, 2013
- [Antigenic diversity of African swine fever viruses].2011
- Protection of European domestic pigs from virulent African isolates of African swine fever virus by experimental immunisationVaccine, 2011
- MEGA5: Molecular Evolutionary Genetics Analysis Using Maximum Likelihood, Evolutionary Distance, and Maximum Parsimony MethodsMolecular Biology and Evolution, 2011
- Enhanced discrimination of African swine fever virus isolates through nucleotide sequencing of the p54, p72, and pB602L (CVR) genesVirus Genes, 2008
- Genotyping field strains of African swine fever virus by partial p72 gene characterisationArchiv für die gesamte Virusforschung, 2003
- An African Swine Fever Virus ERV1-ALR Homologue, 9GL , Affects Virion Maturation and Viral Growth in Macrophages and Viral Virulence in SwineJournal of Virology, 2000
- Clinical and immunologic responses of pigs to African swine fever virus isolated from the Western Hemisphere.1984