Sequence Variants in Kynurenine Aminotransferase II (KAT II) Orthologs Determine Different Potencies of the Inhibitor S‐ESBA
- 11 August 2008
- journal article
- research article
- Published by Wiley in ChemMedChem
- Vol. 3 (8), 1199-1202
- https://doi.org/10.1002/cmdc.200800109
Abstract
No abstract availableKeywords
This publication has 19 references indexed in Scilit:
- Structural Insight into the Mechanism of Substrate Specificity of Aedes Kynurenine Aminotransferase,Biochemistry, 2008
- Immunosuppression Via Tryptophan Catabolism: The Role of Kynurenine Pathway EnzymesTransplantation, 2007
- Mitochondrial aspartate aminotransferase: a third kynurenate‐producing enzyme in the mammalian brainJournal of Neurochemistry, 2007
- Modulators of the Kynurenine Pathway of Tryptophan Metabolism: Synthesis and Preliminary Biological Evaluation of (S)‐4‐(Ethylsulfonyl)benzoylalanine, a Potent and Selective Kynurenine Aminotransferase II (KAT II) InhibitorChemMedChem, 2006
- Manipulation of Brain Kynurenines: Glial Targets, Neuronal Effects, and Clinical OpportunitiesJournal of Pharmacology and Experimental Therapeutics, 2002
- Endogenous kynurenines as targets for drug discovery and developmentNature Reviews Drug Discovery, 2002
- Derivatives of kynurenine as inhibitors of rat brain kynurenine aminotransferaseEuropean Journal of Medicinal Chemistry, 1996
- Cloning and Functional Expression of a Soluble Form of Kynurenine/α -Aminoadipate Aminotransferase from Rat KidneyPublished by Elsevier BV ,1995
- A Glycine Site Associated with N‐Methyl‐d‐Aspartic Acid Receptors: Characterization and Identification of a New Class of AntagonistsJournal of Neurochemistry, 1989
- A Convenient Differential Protection Strategy for Functional Group Manipulation of Aspartic and Glutamic AcidsSynthesis, 1989