A Rewritable, Random-Access DNA-Based Storage System
Open Access
- 18 September 2015
- journal article
- Published by Springer Science and Business Media LLC in Scientific Reports
- Vol. 5 (1), 14138
- https://doi.org/10.1038/srep14138
Abstract
We describe the first DNA-based storage architecture that enables random access to data blocks and rewriting of information stored at arbitrary locations within the blocks. The newly developed architecture overcomes drawbacks of existing read-only methods that require decoding the whole file in order to read one data fragment. Our system is based on new constrained coding techniques and accompanying DNA editing methods that ensure data reliability, specificity and sensitivity of access and at the same time provide exceptionally high data storage capacity. As a proof of concept, we encoded parts of the Wikipedia pages of six universities in the USA and selected and edited parts of the text written in DNA corresponding to three of these schools. The results suggest that DNA is a versatile media suitable for both ultrahigh density archival and rewritable storage applications.This publication has 18 references indexed in Scilit:
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